DDIT3 Antibody

CAT: 0247-OASG07776-100ULSize: 100 µLDry Ice: NoHazardous: No
CAT#:0247-OASG07776-100ULSize:100 µL
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CAS Number
9007-83-4
Gene Name
DNA damage inducible transcript 3
Gene Aliases
CHOP, CEBPZ, CHOP10, CHOP-10, GADD153, AltDDIT3, C/EBPzeta
Gene ID
1649
Accession Number
NP_001181982.1
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic Peptide of CHOP
Target
This gene encodes a member of the CCAAT/enhancer-binding protein (C/EBP) family of transcription factors. The protein functions as a dominant-negative inhibitor by forming heterodimers with other C/EBP members, such as C/EBP and LAP (liver activator protein), and preventing their DNA binding activity. The protein is implicated in adipogenesis and erythropoiesis, is activated by endoplasmic reticulum stress, and promotes apoptosis. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in myxoid liposarcomas or Ewing sarcoma. Multiple alternatively spliced transcript variants encoding two isoforms with different length have been identified.
Clonality
Monoclonal
Type
Monoclonal Antibody
Applications
IHC
Purification
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
1 mg/ml
Format
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Reconstitution
Store at -20C. Avoid repeated freeze/thaw cycles.
Fragment
IgG1
Specificity
CHOP Mouse Monoclonal Antibody (1E1) detects endogenous levels of DDIT3
NCBI Gene Symbol
DDIT3
Host or Source
Mouse
Protein Name
DNA damage-inducible transcript 3 protein
Gene Name URL
DDIT3
Nucleotide Accession Number
NM_001195053.1

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