ACTA1 Antibody

• Gene Name:

  Actin, alpha 1, skeletal muscle

• Gene Aliases:

  ACTA, ASMA, CFTD, MPFD, NEM1, NEM2, NEM3, SHPM, CFTD1, CFTDM

• Gene ID:

  58

• Accession Number:

  NP_001091.1

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Synthetic Peptide of Muscle actin

• Target:

  The product encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Mutations in this gene cause nemaline myopathy type 3, congenital myopathy with excess of thin myofilaments, congenital myopathy with cores, and congenital myopathy with fiber-type disproportion, diseases that lead to muscle fiber defects.

• Clonality:

  Monoclonal

• Type:

  Monoclonal Antibody

• Applications:

  IHC

• Purification:

  The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.

• Assay Protocol:

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Concentration:

  1 mg/ml

• Format:

  Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Reconstitution:

  Store at -20C. Avoid repeated freeze/thaw cycles.

• Fragment:

  IgG1

• Specificity:

  Muscle actin Mouse Monoclonal Antibody (2H3) detects endogenous levels of ACTA1

• NCBI Gene Symbol:

  ACTA1

• Host or Source:

  Mouse

• Protein Name:

  Actin, alpha skeletal muscle

• Gene Name URL:

  ACTA1

• CAS Number:

  9007-83-4

• Nucleotide Accession Number:

  NM_001100.3