NTRK2 Antibody (Phospho-Tyr706/707)

• Gene Name:

  Neurotrophic tyrosine kinase, receptor, type 2

• Gene Aliases:

  OBHD, TRKB, DEE58, trk-B, EIEE58, GP145-TrkB

• Gene ID:

  4915; 18212; 25054

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Synthesized peptide derived from human Trk B around the phosphorylation site of Y706/Y707. Location: 650-730aa.

• Target:

  This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in this gene have been associated with obesity and mood disorders. Alternative splicing results in multiple transcript variants.

• Clonality:

  Polyclonal

• Type:

  Polyclonal Antibody

• Applications:

  IHC

• Purification:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Assay Protocol:

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Concentration:

  1 mg/ml

• Format:

  Liquid. 1 mg/mL in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Reconstitution:

  Store at -20C. Avoid repeated freeze/thaw cycles.

• Molecular Weight:

  91 kDa

• Fragment:

  IgG

• Specificity:

  Phospho-Trk B (Tyr706/Y707) Polyclonal Antibody detects endogenous levels of Trk B protein only when phosphorylated at Y706/Y707.

• NCBI Gene Symbol:

  NTRK2

• Host or Source:

  Rabbit

• Gene Name URL:

  NTRK2

• CAS Number:

  9007-83-4