PKD2 Antibody (Phospho-Ser812)

• Gene Name:

  Polycystic kidney disease 2 (autosomal dominant)

• Gene Aliases:

  PC2, PKD4, Pc-2, APKD2, TRPP2

• Gene ID:

  5311; 18764

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Synthesized peptide derived from human PKD2 around the phosphorylation site of S812. Location: 750-830aa.

• Target:

  This gene encodes a member of the polycystin protein family. The encoded protein is a multi-pass membrane protein that functions as a calcium permeable cation channel, and is involved in calcium transport and calcium signaling in renal epithelial cells. This protein interacts with polycystin 1, and they may be partners in a common signaling cascade involved in tubular morphogenesis. Mutations in this gene are associated with autosomal dominant polycystic kidney disease type 2.

• Clonality:

  Polyclonal

• Type:

  Polyclonal Antibody

• Applications:

  IF

• Purification:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Assay Protocol:

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Concentration:

  1 mg/ml

• Format:

  Liquid. 1 mg/mL in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Reconstitution:

  Store at -20C. Avoid repeated freeze/thaw cycles.

• Molecular Weight:

  97 kDa

• Fragment:

  IgG

• Specificity:

  Phospho-PKD2 (S812) Polyclonal Antibody detects endogenous levels of PKD2S812.

• NCBI Gene Symbol:

  PKD2

• Host or Source:

  Rabbit

• Gene Name URL:

  PKD2

• CAS Number:

  9007-83-4