PAK1 Antibody

• Gene Name:

  P21 protein (Cdc42/Rac) -activated kinase 1

• Gene Aliases:

  IDDMSSD, p65-PAK, PAKalpha, alpha-PAK

• Gene ID:

  5058; 5062; 5063; 224105; 18481; 29431; 100910732; 29433

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Synthesized peptide derived from human PAK Alpha/Beta/Gamma around the non-phosphorylation site of T423/402/421. Location: 360-440aa.

• Target:

  This gene encodes a family member of serine/threonine p21-activating kinases, known as PAK proteins. These proteins are critical effectors that link RhoGTPases to cytoskeleton reorganization and nuclear signaling, and they serve as targets for the small GTP binding proteins Cdc42 and Rac. This specific family member regulates cell motility and morphology. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

• Clonality:

  Polyclonal

• Type:

  Polyclonal Antibody

• Applications:

  WB, IHC

• Purification:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Assay Protocol:

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Concentration:

  1 mg/ml

• Format:

  Liquid. 1 mg/mL in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Reconstitution:

  Store at -20C. Avoid repeated freeze/thaw cycles.

• Molecular Weight:

  62 kDa

• Fragment:

  IgG

• Specificity:

  PAK Alpha/Beta/Gamma Polyclonal Antibody detects endogenous levels of PAK Alpha/Beta/Gamma protein.

• NCBI Gene Symbol:

  LOC100910732, PAK1, PAK2, PAK3

• Host or Source:

  Rabbit

• Gene Name URL:

  LOC100910732PAK1PAK2PAK3

• CAS Number:

  9007-83-4