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NFKB2 Antibody

CAT: 0247-OASG04979-100ULSize: 100 µLDry Ice: NoHazardous: No
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CAT#:0247-OASG04979-100ULSize:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Gene Name
Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
Gene Aliases
P52, p100, H2TF1, LYT10, CVID10, LYT-10, NF-kB2, p49/p100
Gene ID
4791; 18034
Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide derived from human NFKappaB-p100 around the non-phosphorylation site of S865. Location: 810-890aa.
Target
This gene encodes a subunit of the transcription factor complex nuclear factor-kappa-B (NFkB) . The NFkB complex is expressed in numerous cell types and functions as a central activator of genes involved in inflammation and immune function. The protein encoded by this gene can function as both a transcriptional activator or repressor depending on its dimerization partner. The p100 full-length protein is co-translationally processed into a p52 active form. Chromosomal rearrangements and translocations of this locus have been observed in B cell lymphomas, some of which may result in the formation of fusion proteins. There is a pseudogene for this gene on chromosome 18. Alternative splicing results in multiple transcript variants.
Clonality
Polyclonal
Type
Polyclonal Antibody
Applications
WB, IHC, IP, IF
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
1 mg/ml
Format
Liquid. 1 mg/mL in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Reconstitution
Store at -20C. Avoid repeated freeze/thaw cycles.
Molecular Weight
97 kDa
Fragment
IgG
Specificity
NFKappaB-p100 Polyclonal Antibody detects endogenous levels of NFKappaB-p100 protein.
NCBI Gene Symbol
NFKB2
Host or Source
Rabbit
Gene Name URL
NFKB2

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