KRT6B Antibody

• Gene Name:

  Keratin 6B, type II

• Gene Aliases:

  K6B, PC2, PC4, CK6B, CK-6B, KRTL1

• Gene ID:

  3854; 286887; 3853

• Reactivity:

  Human

• Immunogen:

  Synthetic Peptide

• Target:

  The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. As many as six of this type II cytokeratin (KRT6) have been identified; the multiplicity of the genes is attributed to successive gene duplication events. The genes are expressed with family members KRT16 and/or KRT17 in the filiform papillae of the tongue, the stratified epithelial lining of oral mucosa and esophagus, the outer root sheath of hair follicles, and the glandular epithelia. Mutations in these genes have been associated with pachyonychia congenita. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.

• Clonality:

  Monoclonal

• Type:

  Monoclonal Antibody

• Applications:

  WB

• Purification:

  The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.

• Assay Protocol:

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Concentration:

  1 mg/ml

• Format:

  Liquid. 1 mg/mL in PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.

• Reconstitution:

  Store at -20C. Avoid repeated freeze/thaw cycles.

• Specificity:

  The antibody detects endogenous Cytokeratin 6 proteins.

• NCBI Gene Symbol:

  KRT6A, KRT6B, KRT6C

• Host or Source:

  Mouse

• Gene Name URL:

  KRT6AKRT6BKRT6C

• CAS Number:

  9007-83-4