ACACA Antibody

• Gene Name :

  Acetyl-CoA carboxylase alpha

• Gene Aliases :

  ACC, ACAC, ACC1, ACCA, ACACAD

• Gene ID :

  31; 107476; 60581

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Synthesized peptide derived from human ACC Alpha around the non-phosphorylation site of S80. Location: 20-100aa.

• Target :

  Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene.

• Clonality :

  Polyclonal

• Type :

  Polyclonal Antibody

• Applications :

  WB, IHC

• Purification :

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Assay Protocol :

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Concentration :

  1 mg/ml

• Format :

  Liquid.// PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Reconstitution :

  Store at -20C. Avoid repeated freeze/thaw cycles.

• Molecular Weight :

  265 kDa

• Fragment :

  IgG

• Specificity :

  ACC Alpha Polyclonal Antibody detects endogenous levels of ACC Alpha protein.

• NCBI Gene Symbol :

  ACACA

• Host or Source :

  Rabbit

• Gene Name URL :

  ACACA

• CAS Number :

  9007-83-4