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TrpM7 Antibody

CAT: 0247-OASE00166-100UGSize: 100 µgDry Ice: NoHazardous: No
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CAT#:0247-OASE00166-100UGSize:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Gene Name
Transient receptor potential cation channel, subfamily M, member 7
Gene Aliases
CHAK, CHAK1, Channel kinase 1, Channel-kinase 1, Long transient receptor potential channel 7, LTrpC-7, LTRPC7, Transient receptor potential cation channel subfamily M member 7, TRP PLIK, TRPM7, TRPM7_HUMAN
Gene ID
58800
Accession Number
NP_001157797.1
Reactivity
Human, Mouse, Rat
Immunogen
Fusion protein amino acids 1817-1863 (C- terminus) of mouse TrpM7
Target
TRPs, mammalian homologs of the Drosophila transient receptor potential (trp) protein, are ion channels that are thought to mediate capacitative calcium entry into the cell. TRP-PLIK is a protein that is both an ion channel and a kinase. As a channel, it conducts calcium and monovalent cations to depolarize cells and increase intracellular calcium. As a kinase, it is capable of phosphorylating itself and other substrates. The kinase activity is necessary for channel function, as shown by its dependence on intracellular ATP and by the kinase mutants (1, 2) .
Clonality
Monoclonal
Clone
S74
Conjugation
Unconjugated
Type
Monoclonal Antibody
Applications
WB, IHC, ICC, IF, AM
Purification
Protein G Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
1 mg/ml
Dilution
WB (1:1000), IHC (1:1000), ICC/IF (1:100) ; optimal dilutions for assays should be determined by the user.
Format
Liquid.// PBS (pH 7.4) with 50% glycerol and 0.09% sodium azide.
Buffer
PBS pH7.4, 50% glycerol, 0.09% sodium azide
Reconstitution
Store at -20C. Shipping with Blue Ice or 4C.
Molecular Weight
220 kDa
Notes
Formerly GWB-9BAC01
Fragment
IgG1
Specificity
Detects ~220kDa in extracts of cells transiently transfected with TrpM7. No cross-reactivity against TrpM6.
NCBI Gene Symbol
TRPM7
Host or Source
Mouse
Gene Name URL
TRPM7

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