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Human TLR4 Antibody

CAT: 0247-OASB01314-100UGSize: 0.1 mgDry Ice: NoHazardous: No
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CAT#:0247-OASB01314-100UGSize:0.1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Gene Name
Toll-like receptor 4
Gene Aliases
TOLL, CD284, TLR-4, ARMD10
Gene ID
7099
Accession Number
NP_003257.1
Reactivity
Human
Target
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor has been implicated in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria. Mutations in this gene have been associated with differences in LPS responsiveness. Multiple transcript variants encoding different isoforms have been found for this gene.
Clonality
Monoclonal
Clone
100000000000
Conjugation
Unconjugated
Type
Monoclonal Antibody
Applications
WB
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
0.5 mg/mL
Dilution
ELISA: Purified antibody 1:2000-1:4,000
Reconstitution
Store at 2-8C
Notes
Formerly GWB-25DA85
Fragment
IgG2a
Specificity
TLR4
NCBI Gene Symbol
TLR4
Host or Source
Mouse
Protein Name
Toll-like receptor 4
Gene Name URL
TLR4
Nucleotide Accession Number
NM_003266.3

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