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Mouse TNF-a Antibody

CAT: 0247-OASB01272-500UGSize: 0.5 mgDry Ice: NoHazardous: No
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CAT#:0247-OASB01272-500UGSize:0.5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Gene Name
Tumor necrosis factor
Gene Aliases
DI, Tn, DIF, TNF-, Tnfa, Tnfs, TNF-a, TNFSF2, Tnlg1f, Tnfsf1a, TNFalpha, TNF-alpha
Gene ID
21926
Accession Number
NP_001265530.1
Reactivity
Mouse
Immunogen
E. coli-expressed mouse TNF-alpha
Target
This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. Members of this family are classified based on primary sequence, function, and structure. This protein is synthesized as a type-II transmembrane protein and is reported to be cleaved into products that exert distinct biological functions. It plays an important role in the innate immune response as well as regulating homeostasis but is also implicated in diseases of chronic inflammation. In mouse deficiency of this gene is associated with defects in response to bacterial infection, with defects in forming organized follicular dendritic cell networks and germinal centers, and with a lack of primary B cell follicles. Alternative splicing results in multiple transcript variants.
Clonality
Monoclonal
Clone
MP6-XT3
Conjugation
Unconjugated
Type
Monoclonal Antibody
Applications
ELISPOT, FC, IHC-F, IHC-P, WB
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
0.5 mg/mL
Dilution
ELISA: BIOT conjugate 1:1,000-1:2,000
Reconstitution
Store at 2-8C
Notes
Formerly GWB-92FDEE
Fragment
IgG1
Specificity
TNF-a
NCBI Gene Symbol
TNF
Host or Source
Rat
Protein Name
Tumor necrosis factor
Gene Name URL
TNF
Nucleotide Accession Number
NM_001278601.1

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