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Human Bax Antibody

CAT: 0247-OASB01183-100UGSize: 0.1 mgDry Ice: NoHazardous: No
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CAT#:0247-OASB01183-100UGSize:0.1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Gene Name
Apoptosis regulator BAX
Gene Aliases
BCL2L4
Gene ID
581; 718948; 403523; 280730
Accession Number
NP_001278357.1
Reactivity
Human
Immunogen
Human Bax peptide (a.a. 3-16)
Target
The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for this gene.
Clonality
Monoclonal
Clone
2D2
Conjugation
Unconjugated
Type
Monoclonal Antibody
Applications
WB, IP, FC, IHC-P, ICC
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
0.1 mg/mL
Reconstitution
Store at 2-8C
Notes
Formerly GWB-1B6557
Fragment
IgG1
Specificity
Bax
NCBI Gene Symbol
BAX
Host or Source
Mouse
Protein Name
Apoptosis regulator BAX
Gene Name URL
BAX
Nucleotide Accession Number
NM_001291428.1

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