Human CD43 Antibody : SPRD

• Gene Name:

  Leukosialin

• Gene Aliases:

  LSN, CD43, GALGP, GPL115

• Gene ID:

  6693

• Accession Number:

  NP_001025459.1

• Reactivity:

  Human

• Immunogen:

  KG-1 cells

• Target:

  This gene encodes a highly sialylated glycoprotein that functions in antigen-specific activation of T cells, and is found on the surface of thymocytes, T lymphocytes, monocytes, granulocytes, and some B lymphocytes. It contains a mucin-like extracellular domain, a transmembrane region and a carboxy-terminal intracellular region. The extracellular domain has a high proportion of serine and threonine residues, allowing extensive O-glycosylation, and has one potential N-glycosylation site, while the carboxy-terminal region has potential phosphorylation sites that may mediate transduction of activation signals. Different glycoforms of this protein have been described. In stimulated immune cells, proteolytic cleavage of the extracellular domain occurs in some cell types, releasing a soluble extracellular fragment. Defects in expression of this gene are associated with Wiskott-Aldrich syndrome.

• Clonality:

  Monoclonal

• Clone:

  DF-T1

• Conjugation:

  Spectral Red®

• Type:

  Monoclonal Antibody

• Applications:

  FC

• Assay Protocol:

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Concentration:

  Lot specific

• Dilution:

  6 cells 10 uL/106 cells 10 uL/106 cells 10 uL/106 cells 10 uL/106 cells6666

• Reconstitution:

  Store at 2-8C

• Notes:

  Formerly GWB-20F3AB

• Fragment:

  IgG1

• Specificity:

  CD43

• NCBI Gene Symbol:

  SPN

• Host or Source:

  Mouse

• Protein Name:

  Leukosialin

• Gene Name URL:

  SPN

• CAS Number:

  9007-83-4

• Nucleotide Accession Number:

  NM_001030288.2