MDM2 Antibody

CAT: 0247-OASA03475-20UGSize: 20 µgDry Ice: NoHazardous: No
CAT#:0247-OASA03475-20UGSize:20 µg
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CAS Number
9007-83-4
Gene Aliases
PERB11.2
Gene ID
4277
Accession Number
NP_002383.2
Reactivity
Human
Immunogen
Synthetic peptide, CSRPSTSSRRRAISE, corresponding to amino acids 154-167 of human MDM2.
Target
Mouse anti MDM2 antibody, clone SMP14 recognizes the MDM2 protein, which forms a complex with p53 leading to p53 inhibition. MDM2 also acts to stimulate cell proliferation via its induction of transcription factors such as E2F1 and DPI. MDM2 is over expressed in a range of human malignancies, including soft tissue sarcomas, breast cancer and bladder cancer.
Clonality
Monoclonal
Clone
SMP14
Type
Monoclonal Antibody
Applications
Immunohistochemistry-Frozen|Immunohistochemistry-Paraffin|Immunohistochemistry-Resin
Purification
Protein A Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
1 mg/ml
Format
Liquid. Phosphate buffered saline
Reconstitution
-20°C
Molecular Weight
90 kDa
Notes
Formerly GWB-AD54FA
Fragment
IgG1
Specificity
MDM2. Reacts with mouse. Antibody reactivity and working conditions may vary between species.
Protein Length
497
NCBI Gene Symbol
MDM2
Host or Source
Mouse
Protein Name
E3 ubiquitin-protein ligase Mdm2
Gene Name URL
MDM2

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