MDM2 Antibody

• Gene Aliases:

  PERB11.2

• Gene ID:

  4277

• Accession Number:

  NP_002383.2

• Reactivity:

  Human

• Immunogen:

  Synthetic peptide, CSRPSTSSRRRAISE, corresponding to amino acids 154-167 of human MDM2.

• Target:

  Mouse anti MDM2 antibody, clone SMP14 recognizes the MDM2 protein, which forms a complex with p53 leading to p53 inhibition. MDM2 also acts to stimulate cell proliferation via its induction of transcription factors such as E2F1 and DPI. MDM2 is over expressed in a range of human malignancies, including soft tissue sarcomas, breast cancer and bladder cancer.

• Clonality:

  Monoclonal

• Clone:

  SMP14

• Type:

  Monoclonal Antibody

• Applications:

  Immunohistochemistry-Frozen|Immunohistochemistry-Paraffin|Immunohistochemistry-Resin

• Purification:

  Protein A Purified

• Assay Protocol:

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Concentration:

  1 mg/ml

• Format:

  Liquid. Phosphate buffered saline

• Reconstitution:

  -20°C

• Molecular Weight:

  90 kDa

• Notes:

  Formerly GWB-AD54FA

• Fragment:

  IgG1

• Specificity:

  MDM2. Reacts with mouse. Antibody reactivity and working conditions may vary between species.

• Protein Length:

  497

• NCBI Gene Symbol:

  MDM2

• Host or Source:

  Mouse

• Protein Name:

  E3 ubiquitin-protein ligase Mdm2

• Gene Name URL:

  MDM2

• CAS Number:

  9007-83-4