CFB Antibody

• Gene Aliases:

  BF, FB, BFD, GBG, CFAB, CFBD, PBF2, AHUS4, FBI12, H2-Bf, ARMD14

• Gene ID:

  629

• Accession Number:

  NP_001701.2

• Reactivity:

  Human

• Immunogen:

  Purified Human factor B

• Clonality:

  Monoclonal

• Clone:

  032B-22.1.X

• Type:

  Monoclonal Antibody

• Applications:

  Enzyme-linked immunosorbent assay

• Purification:

  Purified IgG prepared by affinity chromatography on Protein A from ascites

• Assay Protocol:

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Concentration:

  1.125 mg/ml

• Homology:

  Human

• Format:

  Liquid. Borate buffered saline

• Reconstitution:

  -20°C

• Notes:

  Formerly GWB-9B6916

• Fragment:

  IgG2a

• Specificity:

  Mouse anti human complement factor Bb neoantigen monoclonal antibody, clone 032B-22.1.X recognizes a neoantigen of the Bb fragment of human complement factor B. Factor B is present in blood serum. C3b associates with complement factor B, inducing conformational change. This enables complement factor D to cleave the N-terminal of complement factor B (the Ba subunit) leaving the 63 kDa Bb subunit associated with C3b and forming C3 convertase. Subunit Bb is involved in the proliferation of preactivated B lymphocytes. Conversely, Ba inhibits lymphocyte proliferation.

• Protein Length:

  764

• NCBI Gene Symbol:

  CFB

• Host or Source:

  Mouse

• Protein Name:

  Complement factor B

• Gene Name URL:

  CFB

• CAS Number:

  9007-83-4