CFB Antibody

CAT: 0247-OASA02635-100UGSize: 0.1 mgDry Ice: NoHazardous: No
CAT#:0247-OASA02635-100UGSize:0.1 mg
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CAS Number
9007-83-4
Gene Aliases
BF, FB, BFD, GBG, CFAB, CFBD, PBF2, AHUS4, FBI12, H2-Bf, ARMD14
Gene ID
629
Accession Number
NP_001701.2
Reactivity
Human
Immunogen
Purified Human factor B
Clonality
Monoclonal
Clone
032B-22.1.X
Type
Monoclonal Antibody
Applications
Enzyme-linked immunosorbent assay
Purification
Purified IgG prepared by affinity chromatography on Protein A from ascites
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
1.125 mg/ml
Homology
Human
Format
Liquid. Borate buffered saline
Reconstitution
-20°C
Notes
Formerly GWB-9B6916
Fragment
IgG2a
Specificity
Mouse anti human complement factor Bb neoantigen monoclonal antibody, clone 032B-22.1.X recognizes a neoantigen of the Bb fragment of human complement factor B. Factor B is present in blood serum. C3b associates with complement factor B, inducing conformational change. This enables complement factor D to cleave the N-terminal of complement factor B (the Ba subunit) leaving the 63 kDa Bb subunit associated with C3b and forming C3 convertase. Subunit Bb is involved in the proliferation of preactivated B lymphocytes. Conversely, Ba inhibits lymphocyte proliferation.
Protein Length
764
NCBI Gene Symbol
CFB
Host or Source
Mouse
Protein Name
Complement factor B
Gene Name URL
CFB

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