CD63 Antibody

• Gene Aliases:

  MLA1, ME491, LAMP-3, OMA81H, TSPAN30

• Gene ID:

  967

• Accession Number:

  NP_001771.1

• Reactivity:

  Human

• Immunogen:

  HPB-ALL cell line.

• Target:

  CD63 is a 238 amino acid, tetraspanin glycoprotein of ~40-60 kDa. CD63 is expressed by monocytes, macrophages, endothelial cells where it is a component of Weibel-Palade bodies and by a variety of cell lines. It is located intracellularly in lysosomal granules of platelets, being translocated to the surface upon activation. It may therefore be useful as a marker of platelet activation. CD63 expression is also associated with melanoma development and expression is rapidly down-regulated by progesterone in endometrial tissues.

• Clonality:

  Monoclonal

• Clone:

  MEM-259

• Type:

  Monoclonal Antibody

• Applications:

  Flow cytometry|Immunofluorescence|Immunoprecipitation

• Purification:

  Protein A Purified

• Assay Protocol:

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Concentration:

  1 mg/ml

• Format:

  Liquid. Phosphate buffered saline

• Reconstitution:

  -20°C

• Notes:

  Formerly GWB-F77981

• Fragment:

  IgG1

• Specificity:

  Mouse anti Human CD63 antibody, clone MEM-259 recognizes the CD63 cell surface antigen, also known as granulophysin, lysozomal associated membrane protein 3 (LAMP-3), Melanoma-associated antigen ME491, Ocular melanoma-associated antigen or tetraspanin-30.

• Protein Length:

  238

• NCBI Gene Symbol:

  CD63

• Host or Source:

  Mouse

• Protein Name:

  CD63 antigen

• Gene Name URL:

  CD63

• CAS Number:

  9007-83-4