PDCD4 Antibody

• CAS Number :

  9007-83-4

• Gene Name :

  Programmed cell death 4

• Gene Aliases :

  H731; neoplastic transformation inhibitor protein; nuclear antigen H731; Nuclear antigen H731-like; programmed cell death 4 (neoplastic transformation inhibitor) ; programmed cell death protein 4; protein 197/15a.

• Gene ID :

  27250

• Accession Number :

  NP_055271.2NP_663314.1

• Reactivity :

  Human|Mouse

• Immunogen :

  This monoclonal antibody was produced by repeated immunizations with a synthetic peptide corresponding to residues surrounding Ser457 of the human Pdcd4 protein.

• Target :

  Inhibits translation initiation and cap-dependent translation. May excert its function by hindering the interaction between EIF4A1 and EIF4G. Inhibits the helicase activity of EIF4A. Modulates the activation of JUN kinase. Down-regulates the expression of MAP4K1, thus inhibiting events important in driving invasion, namely, MAPK85 activation and consequent JUN-dependent transcription. May play a role in apoptosis. Tumor suppressor. Inhibits tumor promoter-induced neoplastic transformation. Binds RNA (By similarity) .

• Clonality :

  Monoclonal

• Clone :

  9G6

• Conjugation :

  Unconjugated

• Type :

  Monoclonal Antibody

• Applications :

  Enzyme-linked immunosorbent assay|Immunohistochemistry|Western blot

• Assay Protocol :

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Concentration :

  1 mg/ml

• Homology :

  Human; Mouse; Rat

• Format :

  Liquid (sterile filtered)

• Reconstitution :

  -20°C|See manual

• NCBI Gene Symbol :

  PDCD4

• Host or Source :

  Mouse

• Protein Name :

  Programmed cell death protein 4

• Gene Name URL :

  PDCD4

• Nucleotide Accession Number :

  NM_014456.4NM_145341.3