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PDCD4 Antibody

CAT: 0247-OARA02819-25ULSize: 25 µLDry Ice: NoHazardous: No
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CAT#:0247-OARA02819-25ULSize:25 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Gene Name
Programmed cell death 4
Gene Aliases
H731; neoplastic transformation inhibitor protein; nuclear antigen H731; Nuclear antigen H731-like; programmed cell death 4 (neoplastic transformation inhibitor) ; programmed cell death protein 4; protein 197/15a.
Gene ID
27250
Accession Number
NP_055271.2NP_663314.1
Reactivity
Human|Mouse
Immunogen
This monoclonal antibody was produced by repeated immunizations with a synthetic peptide corresponding to residues surrounding Ser457 of the human Pdcd4 protein.
Target
Inhibits translation initiation and cap-dependent translation. May excert its function by hindering the interaction between EIF4A1 and EIF4G. Inhibits the helicase activity of EIF4A. Modulates the activation of JUN kinase. Down-regulates the expression of MAP4K1, thus inhibiting events important in driving invasion, namely, MAPK85 activation and consequent JUN-dependent transcription. May play a role in apoptosis. Tumor suppressor. Inhibits tumor promoter-induced neoplastic transformation. Binds RNA (By similarity) .
Clonality
Monoclonal
Clone
9G6
Conjugation
Unconjugated
Type
Monoclonal Antibody
Applications
Enzyme-linked immunosorbent assay|Immunohistochemistry|Western blot
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
1 mg/ml
Homology
Human; Mouse; Rat
Format
Liquid (sterile filtered)
Reconstitution
-20°C|See manual
NCBI Gene Symbol
PDCD4
Host or Source
Mouse
Protein Name
Programmed cell death protein 4
Gene Name URL
PDCD4
Nucleotide Accession Number
NM_014456.4NM_145341.3

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