Anti-GluR1

• Gene Aliases:

  GluA1, gluR-A

• Gene ID:

  50592

• Accession Number:

  NP_113796.1

• Reactivity:

  Mouse, Rat

• Immunogen:

  Peptide corresponding to amino acid residues from the N-terminal region of rat GluR1.

• Target:

  The ion channels activated by glutamate are typically divided into two classes. Those that are sensitive to N-methyl-D-aspartate (NMDA) are designated NMDA receptors (NMDAR) while those activated by alpha -amino-3-hydroxy-5-methyl-4-isoxalone propionic acid (AMPA) are known as AMPA receptors (AMPAR) . The AMPAR are comprised of four distinct glutamate receptor subunits designated (GluR1-4) and they play key roles in virtually all excitatory neurotransmission in the brain (Keinänen et al., 1990; Hollmann and Heinemann, 1994) .

• Clonality:

  Monoclonal

• Clone:

  RH95

• Type:

  Monoclonal Antibody

• Applications:

  WB

• Purification:

  Protein G purified culture supernatant.

• Assay Protocol:

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Homology:

  Mouse; Rat

• Format:

  Liquid. 100 ul in 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 ug per ml BSA and 50% glycerol. Adequate amount of material to conduct 10-mini Western Blots.

• Reconstitution:

  Store at -20C; stable for at least one year.

• Molecular Weight:

  ~105kDa

• Fragment:

  2a

• Specificity:

  Specific for the ~105k GluR1 protein.

• NCBI Gene Symbol:

  GRIA1

• Host or Source:

  Mouse

• Protein Name:

  Glutamate receptor 1

• Gene Name URL:

  GRIA1

• CAS Number:

  9007-83-4