TSHZ3 Antibody - N-terminal

• Gene Name:

  Teashirt zinc finger homeobox 3

• Gene Aliases:

  Teashirt family zinc finger 3; teashirt homolog 3; TSH3; zinc finger protein 537; ZNF537.

• Gene ID:

  57616

• Accession Number:

  https://www.ncbi.nlm.nih.gov/protein/NP_065907

• Reactivity:

  Human|Mouse|Rat

• Immunogen:

  TSHZ3 antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human TSHZ3. The immunogen is located within amino acids 60 - 110 of TSHZ3.

• Target:

  Transcriptional regulator involved in developmental processes. Function in association with APBB1, SET and HDAC factors as a transcriptional repressor, that inhibits the expression of CASP4. TSHZ3-mediated transcription repression involves the recruitment of histone deacetylases HDAC1 and HDAC2. Associates with chromatin in a region surrounding the CASP4 transcriptional start site (s) (PubMed:19343227) . Regulates the development of neurons involved in both respiratory rhythm and airflow control. Promotes maintenance of nucleus ambiguus (nA) motoneurons, which govern upper airway function, and establishes a respiratory rhythm generator (RRG) activity compatible with survival at birth. Involved in the differentiation of the proximal uretic smooth muscle cells during developmental processes. Involved in the up-regulation of myocardin, that directs the expression of smooth muscle cells in the proximal ureter (By similarity) . Involved in the modulation of glutamatergic synaptic transmission and long-term synaptic potentiation (By similarity) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  Enzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry-Paraffin|Western blot

• Purification:

  Affinity Purified

• Assay Protocol:

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Concentration:

  1 mg/ml

• Format:

  Liquid. TSHZ3 Antibody is supplied in PBS containing 0.02% sodium azide.

• Reconstitution:

  For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

• Fragment:

  IgG

• NCBI Gene Symbol:

  TSHZ3

• Host or Source:

  Rabbit

• Protein Name:

  Teashirt homolog 3|teashirt homolog 3 [Homo sapiens]

• Gene Name URL:

  TSHZ3

• CAS Number:

  9007-83-4

• Nucleotide Accession Number:

  NM_020856.2