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NA Antibody

CAT: 0247-OAPB01366-100UGSize: 0.1 mgDry Ice: NoHazardous: No
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CAT#:0247-OAPB01366-100UGSize:0.1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
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CAS Number
9007-83-4
Gene Name
Neuraminidase
Accession Number
https://www.ncbi.nlm.nih.gov/protein/ACA33620
Reactivity
Influenza A Virus|Virus
Immunogen
Mouse monoclonal neuraminidase antibody was raised against a synthetic peptide from the seasonal influenza (H1N1) neuraminidase protein.
Target
Catalyzes the removal of terminal sialic acid residues from viral and cellular glycoconjugates. Cleaves off the terminal sialic acids on the glycosylated HA during virus budding to facilitate virus release. Additionally helps virus spread through the circulation by further removing sialic acids from the cell surface. These cleavages prevent self-aggregation and ensure the efficient spread of the progeny virus from cell to cell. Otherwise, infection would be limited to one round of replication. Described as a receptor-destroying enzyme because it cleaves a terminal sialic acid from the cellular receptors. May facilitate viral invasion of the upper airways by cleaving the sialic acid moities on the mucin of the airway epithelial cells. Likely to plays a role in the budding process through its association with lipid rafts during intracellular transport. May additionally display a raft-association independent effect on budding. Plays a role in the determination of host range restriction on replication and virulence. Sialidase activity in late endosome/lysosome traffic seems to enhance virus replication.
Clonality
Monoclonal
Conjugation
Unconjugated
Type
Monoclonal Antibody
Applications
Enzyme-linked immunosorbent assay
Purification
Protein A Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
1 mg/ml
Homology
Virus
Format
Liquid. Seasonal H1N1 Neuraminidase Monoclonal Antibody is supplied in PBS containing 0.02% sodium azide.
Reconstitution
Seasonal H1N1 Neuraminidase monoclonal antibody can be stored at 4C, stable for one year.
NCBI Gene Symbol
NA
Protein Name
Neuraminidase|neuraminidase [Influenza A virus (A/Georgia/20/2006 (H1N1) ) ]
Gene Name URL
NA

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