GLS2 Antibody

• Gene Name:

  Glutaminase 2

• Gene Aliases:

  Breast cell glutaminase; GA; GLS; glutaminase 2 (liver, mitochondrial) ; glutaminase I; glutaminase liver isoform, mitochondrial; hLGA; LGA; L-glutaminase; L-glutamine amidohydrolase; phosphate-activated glutaminase; phosphate-dependent glutaminase.

• Gene ID:

  27165

• Accession Number:

  https://www.ncbi.nlm.nih.gov/protein/NP_037399

• Reactivity:

  Human|Mouse|Rat

• Immunogen:

  GLS2 antibody was raised against an 18 amino acid synthetic peptide near the center terminus of human GLS2. The immunogen is located within amino acids 300 - 350 of GLS2.

• Target:

  Plays an important role in the regulation of glutamine catabolism. Promotes mitochondrial respiration and increases ATP generation in cells by catalyzing the synthesis of glutamate and alpha-ketoglutarate. Increases cellular anti-oxidant function via NADH and glutathione production. May play a role in preventing tumor proliferation.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  Enzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry-Paraffin|Western blot

• Purification:

  Affinity Purified

• Assay Protocol:

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Concentration:

  1 mg/ml

• Homology:

  Rat

• Format:

  Liquid. GLS2 Antibody is supplied in PBS containing 0.02% sodium azide.

• Reconstitution:

  2°C to 8°C

• Molecular Weight:

  Predicted: 36, 55, 62, 66 kDa Observed: 55, 62 kDa

• Specificity:

  GLS2 antibody is predicted to not cross-react with other catenin family members. Multiple isoforms of GLS2 are known to exist.

• NCBI Gene Symbol:

  GLS2

• Host or Source:

  Rabbit

• Protein Name:

  Glutaminase liver isoform, mitochondrial|glutaminase liver isoform, mitochondrial isoform 1 precursor [Homo sapiens]

• Gene Name URL:

  GLS2

• CAS Number:

  9007-83-4