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VLK Antibody

CAT: 0247-OAPB01023-100UGSize: 0.1 mgDry Ice: NoHazardous: No
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CAT#:0247-OAPB01023-100UGSize:0.1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Gene Name
Protein kinase domain containing, cytoplasmic
Gene Aliases
Adtk; Adtk1; AI115348; AW548124; ESTM1; ESTM17; extracellular tyrosine-protein kinase PKDCC; MAd; MAd1; protein kinase domain containing, cytoplasmic homolog; protein kinase domain-containing protein, cytoplasmic; protein kinase-like protein SgK493; RLSDF; Sgk493; sugen kinase 493; V; vertebrate lonesome kinase; Vlk; X83346.
Gene ID
106522|91461
Accession Number
https://www.ncbi.nlm.nih.gov/protein/NP_612379
Reactivity
Human|Mouse|Rat
Immunogen
VLK antibody was raised against a 15 amino acid synthetic peptide from near the center of human VLK. The immunogen is located within amino acids 320 - 370 of VLK.
Target
Secreted tyrosine-protein kinase that mediates phosphorylation of extracellular proteins and endogenous proteins in the secretory pathway, which is essential for patterning at organogenesis stages. Mediates phosphorylation of MMP1, MMP13, MMP14, MMP19 and ERP29 (PubMed:25171405) . May also have serine/threonine protein kinase activity (PubMed:25171405) . Required for longitudinal bone growth through regulation of chondrocyte differentiation (PubMed:19097194, PubMed:23792766) . May be indirectly involved in protein transport from the Golgi apparatus to the plasma membrane (PubMed:19465597) . Probably plays a role in platelets: rapidly and quantitatively secreted from platelets in response to stimulation of platelet degranulation (PubMed:25171405) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
Enzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry-Paraffin|Western blot
Purification
Affinity Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
1 mg/ml
Homology
Human; Mouse; Rat
Format
Liquid. VLK Antibody is supplied in PBS containing 0.02% sodium azide.
Reconstitution
VLK antibody can be stored at 4C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Molecular Weight
Predicted: 32, 54 kDa Observed: 31, 55 kDa
NCBI Gene Symbol
Pkdcc|PKDCC
Host or Source
Rabbit
Protein Name
Extracellular tyrosine-protein kinase PKDCC|extracellular tyrosine-protein kinase PKDCC precursor [Homo sapiens]
Gene Name URL
Pkdcc|PKDCC

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