ANO2 Antibody

• Gene Name:

  Anoctamin 2

• Gene Aliases:

  Anoctamin 2, calcium activated chloride channel; anoctamin-2; C12orf3; TMEM16B; Transmembrane protein 16B; transmembrane protein 16B (eight membrane-spanning domains) .

• Gene ID:

  57101

• Accession Number:

  https://www.ncbi.nlm.nih.gov/protein/NP_001265525

• Reactivity:

  Human|Mouse|Rat

• Immunogen:

  TMEM16B antibody was raised against a 19 amino acid synthetic peptide from near the amino terminus of human TMEM16B. The immunogen is located within the first 50 amino acids of TMEM16B.

• Target:

  Calcium-activated chloride channel (CaCC) which may play a role in olfactory signal transduction. Odorant molecules bind to odor-sensing receptors (OSRs), leading to an increase in calcium entry that activates CaCC current which amplifies the depolarization of the OSR cells, ANO2 seems to be the underlying chloride channel involved in this process. May mediate light perception amplification in retina.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  Enzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry-Paraffin|Western blot

• Purification:

  Affinity Purified

• Assay Protocol:

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Concentration:

  1 mg/ml

• Homology:

  Human; Mouse; Rat

• Format:

  Liquid. TMEM16B Antibody is supplied in PBS containing 0.02% sodium azide.

• Reconstitution:

  2°C to 8°C

• Molecular Weight:

  Predicted: 110 kDa Observed: 107 kDa

• NCBI Gene Symbol:

  ANO2

• Host or Source:

  Rabbit

• Protein Name:

  Anoctamin-2|anoctamin-2 isoform 1 [Homo sapiens]

• Gene Name URL:

  ANO2

• CAS Number:

  9007-83-4

• Nucleotide Accession Number:

  NM_001278596.1NM_001278597.1