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ANO2 Antibody

CAT: 0247-OAPB00972-100UGSize: 0.1 mgDry Ice: NoHazardous: No
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CAT#:0247-OAPB00972-100UGSize:0.1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Gene Name
Anoctamin 2
Gene Aliases
Anoctamin 2, calcium activated chloride channel; anoctamin-2; C12orf3; TMEM16B; Transmembrane protein 16B; transmembrane protein 16B (eight membrane-spanning domains) .
Gene ID
57101
Accession Number
https://www.ncbi.nlm.nih.gov/protein/NP_001265525
Reactivity
Human|Mouse|Rat
Immunogen
TMEM16B antibody was raised against a 19 amino acid synthetic peptide from near the amino terminus of human TMEM16B. The immunogen is located within the first 50 amino acids of TMEM16B.
Target
Calcium-activated chloride channel (CaCC) which may play a role in olfactory signal transduction. Odorant molecules bind to odor-sensing receptors (OSRs), leading to an increase in calcium entry that activates CaCC current which amplifies the depolarization of the OSR cells, ANO2 seems to be the underlying chloride channel involved in this process. May mediate light perception amplification in retina.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
Enzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry-Paraffin|Western blot
Purification
Affinity Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
1 mg/ml
Homology
Human; Mouse; Rat
Format
Liquid. TMEM16B Antibody is supplied in PBS containing 0.02% sodium azide.
Reconstitution
2°C to 8°C
Molecular Weight
Predicted: 110 kDa Observed: 107 kDa
NCBI Gene Symbol
ANO2
Host or Source
Rabbit
Protein Name
Anoctamin-2|anoctamin-2 isoform 1 [Homo sapiens]
Gene Name URL
ANO2
Nucleotide Accession Number
NM_001278596.1NM_001278597.1

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