FNIP2 Antibody

• Gene Name:

  Folliculin interacting protein 2

• Gene Aliases:

  FNIP1-like protein; FNIPL; folliculin-interacting protein 2; MAPO1; O6-methylguanine-induced apoptosis 1 protein.

• Gene ID:

  57600

• Accession Number:

  https://www.ncbi.nlm.nih.gov/protein/NP_065891

• Reactivity:

  Human|Mouse|Rat

• Immunogen:

  FNIP2 antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human FNIP2. The immunogen is located within amino acids 100 - 150 of FNIP2.

• Target:

  Acts as a co-chaperone of HSP90AA1. Inhibits the ATPase activity of HSP90AA1 leading to reduction in its chaperone activity. Facilitates the binding of client protein FLCN to HSP90AA1 (PubMed:27353360) . May play a role in the signal transduction pathway of apoptosis induced by O6-methylguanine-mispaired lesions (By similarity) . May be involved in energy and/or nutrient sensing through the AMPK and mTOR signaling pathways (PubMed:18403135) . May regulate phosphorylation of RPS6KB1 (PubMed:18663353) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  Enzyme-linked immunosorbent assay|Western blot

• Purification:

  Affinity Purified

• Assay Protocol:

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Concentration:

  1 mg/ml

• Homology:

  Human; Mouse; Rat

• Format:

  Liquid. FNIP2 Antibody is supplied in PBS containing 0.02% sodium azide.

• Reconstitution:

  FNIP2 antibody can be stored at 4C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• NCBI Gene Symbol:

  FNIP2

• Host or Source:

  Rabbit

• Protein Name:

  Folliculin-interacting protein 2|folliculin-interacting protein 2 isoform 1 [Homo sapiens]

• Gene Name URL:

  FNIP2

• CAS Number:

  9007-83-4

• Nucleotide Accession Number:

  NM_020840.1XM_005263159.1