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FNIP2 Antibody

CAT: 0247-OAPB00841-100UGSize: 0.1 mgDry Ice: NoHazardous: No
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CAT#:0247-OAPB00841-100UGSize:0.1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Gene Name
Folliculin interacting protein 2
Gene Aliases
FNIP1-like protein; FNIPL; folliculin-interacting protein 2; MAPO1; O6-methylguanine-induced apoptosis 1 protein.
Gene ID
57600
Accession Number
https://www.ncbi.nlm.nih.gov/protein/NP_065891
Reactivity
Human|Mouse|Rat
Immunogen
FNIP2 antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human FNIP2. The immunogen is located within amino acids 100 - 150 of FNIP2.
Target
Acts as a co-chaperone of HSP90AA1. Inhibits the ATPase activity of HSP90AA1 leading to reduction in its chaperone activity. Facilitates the binding of client protein FLCN to HSP90AA1 (PubMed:27353360) . May play a role in the signal transduction pathway of apoptosis induced by O6-methylguanine-mispaired lesions (By similarity) . May be involved in energy and/or nutrient sensing through the AMPK and mTOR signaling pathways (PubMed:18403135) . May regulate phosphorylation of RPS6KB1 (PubMed:18663353) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
Enzyme-linked immunosorbent assay|Western blot
Purification
Affinity Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
1 mg/ml
Homology
Human; Mouse; Rat
Format
Liquid. FNIP2 Antibody is supplied in PBS containing 0.02% sodium azide.
Reconstitution
FNIP2 antibody can be stored at 4C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
NCBI Gene Symbol
FNIP2
Host or Source
Rabbit
Protein Name
Folliculin-interacting protein 2|folliculin-interacting protein 2 isoform 1 [Homo sapiens]
Gene Name URL
FNIP2
Nucleotide Accession Number
NM_020840.1XM_005263159.1

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