Products for Research Use Only
RegisterLogin

STEAP1 Antibody

CAT: 0247-OAPB00561-100UGSize: 0.1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0247-OAPB00561-100UGSize:0.1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
STEAP1 Antibody: The six-transmembrane epithelial antigen of prostate 1 (STEAP1) was the first member of a family of metalloreductases identified as cell-surface antigens in prostate tissue. The normal function of STEAP is still uncertain; unlike other members of the STEAP family, STEAP1 does not promote iron or copper reduction or uptake and lacks the FNO-like reductase domain critical for activity. However, its expression is highly increased in multiple cancer cell lines, including prostate, bladder, colon, and ovarian cancers. Supporting this is evidence that STEAP1 peptides can be used to stimulate CD8+ T cells from healthy donors, enabling them to recognize STEAP1-positive human tumor cells, suggesting that STEAP1 may a potential target for cancer immunotherapy. At least three isoforms of STEAP1 are known to exist.
CAS Number
9007-83-4
Gene Name
STEAP family member 1
Gene Aliases
Metalloreductase STEAP1; PRSS24; six transmembrane epithelial antigen of the prostate 1; six-transmembrane epithelial antigen of prostate 1; STEAP; STEAP1 metalloreductase.
Gene ID
26872
Accession Number
https://www.ncbi.nlm.nih.gov/protein/EAL24166
Reactivity
Human|Mouse|Porcine|Rat
Immunogen
STEAP1 antibody was raised against a 18 amino acid synthetic peptide from near the carboxy terminus of human STEAP1. The immunogen is located within the last 50 amino acids of STEAP1.
Target
Metalloreductase that has the ability to reduce both Fe (3+) to Fe (2+) and Cu (2+) to Cu (1+) . Uses NAD (+) as acceptor (By similarity) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
Enzyme-linked immunosorbent assay|Immunohistochemistry-Paraffin|Western blot
Purification
Affinity Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
1 mg/ml
Homology
Pig (94%)
Format
Liquid. STEAP1 Antibody is supplied in PBS containing 0.02% sodium azide.
Reconstitution
STEAP1 antibody can be stored at 4° C for three months and -20° C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Fragment
IgG
Specificity
This STEAP1 antibody does not cross-react with other STEAP proteins.
NCBI Gene Symbol
STEAP1
Host or Source
Rabbit
Protein Name
Metalloreductase STEAP1|similar to Six transmembrane epithelial antigen of prostate [Homo sapiens]
Gene Name URL
STEAP1

Related Products

CatalogName
OCOA02015-20UGSTEAP1 Protein Lysate
OPCA05312-20UGSTEAP1 Recombinant Protein (Human)
OPCA05312-100UGSTEAP1 Recombinant Protein (Human)
OKEH04337-96WSTEAP1 ELISA Kit (Human)
OKEH05809-96WSTEAP1 ELISA Kit (Mouse)
OPCA02573-1MGOPCA02573-1MG - STEAP1 Recombinant Protein
OKEH05809STEAP1 ELISA Kit (Mouse) (OKEH05809)
OPCA02573-20UGOPCA02573-20UG - STEAP1 Recombinant Protein
OKEH04337STEAP1 ELISA Kit (Human) (OKEH04337)
OPCA02573-100UGOPCA02573-100UG - STEAP1 Recombinant Protein

Alternative Products

CatalogName
abx109996-01Metalloreductase STEAP1 (STEAP1) Antibody
A07506Anti-Metalloreductase STEAP1 STEAP1 Antibody
abx117553Metalloreductase STEAP1 (STEAP1) Antibody Pair
10R-1109STEAP1 antibody

Popular Products