PTGDR2 Antibody

• Description :

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• Gene Name :

  Prostaglandin D2 receptor 2

• Gene Aliases :

  CD294; chemoattractant receptor homologous molecule expressed on T helper type 2 cells; chemoattractant receptor-homologous molecule expressed on TH2 cells; CRTH2; DL1R; DP2; GPR44; G-protein coupled receptor 44; prostaglandin D2 receptor 2; putative G-protein coupled receptor 44.

• Gene ID :

  11251

• Accession Number :

  https://www.ncbi.nlm.nih.gov/protein/NP_004769

• Reactivity :

  Human|Mouse|Rat

• Immunogen :

  CRTH2 antibody was raised against a 15 amino acid synthetic peptide from near the center of human CRTH2. The immunogen is located within amino acids 220 - 270 of CRTH2.

• Target :

  Receptor for prostaglandin D2 (PGD2) . Coupled to the G (i) -protein. Receptor activation may result in pertussis toxin-sensitive decreases in cAMP levels and Ca (2+) mobilization. PI3K signaling is also implicated in mediating PTGDR2 effects. PGD2 induced receptor internalization. CRTH2 internalization can be regulated by diverse kinases such as, PKC, PKA, GRK2, GPRK5/GRK5 and GRK6. Receptor activation is responsible, at least in part, in immune regulation and allergic/inflammation responses.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Polyclonal Antibody

• Applications :

  Enzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry-Paraffin|Western blot

• Purification :

  Affinity Purified

• Assay Protocol :

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Concentration :

  1 mg/ml

• Homology :

  Human; Mouse; Rat

• Format :

  Liquid. CRTH2 Antibody is supplied in PBS containing 0.02% sodium azide.

• Reconstitution :

  CRTH2 antibody can be stored at 4C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• NCBI Gene Symbol :

  PTGDR2

• Host or Source :

  Rabbit

• Protein Name :

  Prostaglandin D2 receptor 2|prostaglandin D2 receptor 2 [Homo sapiens]

• Gene Name URL :

  PTGDR2

• CAS Number :

  9007-83-4

• Nucleotide Accession Number :

  NM_004778.2