CASP7 Antibody

• Gene Name:

  Caspase 7

• Gene Aliases:

  Apoptotic protease MCH-3; CASP-7; caspase 7, apoptosis-related cysteine peptidase; caspase 7, apoptosis-related cysteine protease; caspase-7; CMH-1; ICE-LAP3; ICE-like apoptotic protease 3; LICE2; MCH3.

• Gene ID:

  840

• Accession Number:

  NP_001218.1NP_001253985.1NP_001253986.1NP_001253987.1NP_203124.1NP_203125.1NP_203126

• Reactivity:

  Human|Mouse|Rat

• Immunogen:

  Caspase-7 antibody was raised against a 16 amino acid synthetic peptide from near the amino-terminus of human Caspase-7. The immunogen is located within amino acids 30 - 80 of Caspase-7.

• Target:

  Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves and activates sterol regulatory element binding proteins (SREBPs) . Proteolytically cleaves poly (ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Overexpression promotes programmed cell death.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  Enzyme-linked immunosorbent assay|Immunohistochemistry-Paraffin|Western blot

• Purification:

  Affinity Purified

• Assay Protocol:

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Concentration:

  1 mg/ml

• Homology:

  Human; Mouse; Rat

• Format:

  Liquid. Caspase-7 Antibody is supplied in PBS containing 0.02% sodium azide.

• Reconstitution:

  Caspase-7 antibody can be stored at 4C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Notes:

  Formerly GWB-5958CA

• NCBI Gene Symbol:

  CASP7

• Host or Source:

  Rabbit

• Protein Name:

  Caspase-7

• Gene Name URL:

  CASP7

• CAS Number:

  9007-83-4

• Nucleotide Accession Number:

  NM_001227.4NM_001267056.1NM_001267057.1NM_001267058.1NM_033338.5NM_033339.4