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HA Antibody

CAT: 0247-OAPB00272-100UGSize: 0.1 mgDry Ice: NoHazardous: No
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CAT#:0247-OAPB00272-100UGSize:0.1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Gene Name
Hemagglutinin
Accession Number
https://www.ncbi.nlm.nih.gov/protein/AAT76166
Reactivity
Influenza A Virus|Virus
Immunogen
Avian influenza hemagglutinin antibody was raised against a synthetic peptide corresponding to 14 amino acids in the middle of the avian influenza hemagglutinin protein. Efforts were made to use relatively conserved regions of the viral sequence as the antigen. The immunogen is located within amino acids 320 - 370 of Avian Influenza Hemagglutinin.
Target
Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell. This attachment induces virion internalization either through clathrin-dependent endocytosis or through clathrin- and caveolin-independent pathway. Plays a major role in the determination of host range restriction and virulence. Class I viral fusion protein. Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane. Low pH in endosomes induces an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide. Several trimers are required to form a competent fusion pore.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
Enzyme-linked immunosorbent assay
Purification
Affinity Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
1 mg/ml
Homology
Virus
Format
Liquid. Avian Influenza Hemagglutinin Antibody is supplied in PBS containing 0.02% sodium azide.
Reconstitution
Avian Influenza Hemagglutinin antibody can be stored at 4C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
NCBI Gene Symbol
HA
Host or Source
Rabbit
Protein Name
Hemagglutinin|hemagglutinin [Influenza A virus (A/chicken/Jilin/9/2004 (H5N1) ) ]
Gene Name URL
HA

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