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DIABLO Antibody

CAT: 0247-OAPB00134-100UGSize: 0.1 mgDry Ice: NoHazardous: No
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CAT#:0247-OAPB00134-100UGSize:0.1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Gene Name
Diablo, IAP-binding mitochondrial protein
Gene Aliases
0610041G12Rik;1700006L01Rik; AU040403; diablo homolog, mitochondrial; direct IAP binding protein with low PI; direct IAP-binding protein with low pI; second mitochondria-derived activator of caspase; Sm; Smac.
Gene ID
66593
Accession Number
NP_001265231.1NP_001265232.1NP_001265233.1NP_001265271.1NP_063940.1NP_620308.1
Reactivity
Human|Mouse|Rat
Immunogen
Anti-Smac antibody (2411) was raised against a peptide corresponding to 16 amino acids near the carboxy terminus of murine Smac. The immunogen is located within the last 50 amino acids of Smac.
Target
Promotes apoptosis by activating caspases in the cytochrome c/Apaf-1/caspase-9 pathway. Acts by opposing the inhibitory activity of inhibitor of apoptosis proteins (IAP) . Inhibits the activity of BIRC6/bruce by inhibiting its binding to caspases (By similarity) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
Enzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry-Paraffin|Immunoprecipitation|Western blot
Purification
Affinity Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
1 mg/ml
Homology
Human; Mouse; Rat
Format
Liquid. Smac Antibody is supplied in PBS containing 0.02% sodium azide.
Reconstitution
Smac antibody can be stored at 4C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Molecular Weight
Predicted: 27kD Observed: 20 kD
Notes
Formerly GWB-4295F4
NCBI Gene Symbol
Diablo
Host or Source
Rabbit
Protein Name
Diablo homolog, mitochondrial|Mus musculus direct IAP binding protein with low PI mRNA, complete cds
Gene Name URL
Diablo
Nucleotide Accession Number
https://www.ncbi.nlm.nih.gov/nuccore/AF203914

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