PLP Antibody

• Gene Aliases:

  PLP, PMD, HLD1, MMPL, SPG2, GPM6C, PLP/DM20

• Gene ID:

  5354

• Immunogen:

  S_x005F ynthetic pPLP 139-151.

• Target:

  Lipophilin is a transmembrane proteolipid protein that is the predominant myelin protein present in the central nervous system. PLP functions in myelination. plays a role in the compaction, stabilization, and maintenance of myelin sheaths, as well as in oligodendrocyte development and axonal survival. Mutations associated with PLP gene cause X-linked Pelizaeus-Merzbacher disease and spastic paraplegia type 2. Two transcript variants encoding distinct isoforms have been identified for PLP gene.PLP is the major myelin protein from the central nervous system and plays an important role in the formation or maintenance of the multilamellar structure of myelin.

• Clonality:

  Monoclonal

• Clone:

  NYRPLP.

• Type:

  Monoclonal Antibody

• Applications:

  WB, IP, IHC

• Purification:

  Ion exchange column.

• Assay Protocol:

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Format:

  Lyophilized.

• Reconstitution:

  Shipping Conditions: //Antibody is shipped lyophilized at ambient temperature.

• Notes:

  Formerly GWB-F03E95

• Fragment:

  Mouse IgG1.

• NCBI Gene Symbol:

  PLP1

• Host or Source:

  Mouse

• Protein Name:

  Myelin proteolipid protein

• Gene Name URL:

  PLP1

• CAS Number:

  9007-83-4