RBBP4 Antibody

• Gene Name:

  RB binding protein 4, chromatin remodeling factor

• Gene Aliases:

  NURF55, RBAP48, lin-53

• Gene ID:

  5928

• Accession Number:

  NP_001128727.1

• Reactivity:

  Human

• Immunogen:

  The complete coding region (amino acids 1-425) of RbAp48 expressed in E. coli.

• Target:

  This gene encodes a ubiquitously expressed nuclear protein which belongs to a highly conserved subfamily of WD-repeat proteins. It is present in protein complexes involved in histone acetylation and chromatin assembly. It is part of the Mi-2 complex which has been implicated in chromatin remodeling and transcriptional repression associated with histone deacetylation. This encoded protein is also part of co-repressor complexes, which is an integral component of transcriptional silencing. It is found among several cellular proteins that bind directly to retinoblastoma protein to regulate cell proliferation. This protein also seems to be involved in transcriptional repression of E2F-responsive genes. Three transcript variants encoding different isoforms have been found for this gene.

• Clonality:

  Monoclonal

• Clone:

  13D10

• Type:

  Monoclonal Antibody

• Applications:

  ICC, IF, IHC, WB

• Purification:

  Protein G purified

• Assay Protocol:

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Concentration:

  1 mg/ml

• Format:

  Liquid

• Buffer:

  Phosphate-buffered saline, pH 7.4, containing no preservatives

• Reconstitution:

  Keep as concentrated solution. Store at 4C short term. For extended storage aliquot and store at -20C or below. Avoid freeze-thaw cycles.

• Fragment:

  IgG2b

• NCBI Gene Symbol:

  RBBP4

• Host or Source:

  Mouse

• Protein Name:

  Histone-binding protein RBBP4

• Gene Name URL:

  RBBP4

• CAS Number:

  9007-83-4

• Nucleotide Accession Number:

  NM_001135255.1