BRCA2 Antibody

CAT: 0247-OAGA08728-100ULSize: 100 µLDry Ice: NoHazardous: No
CAT#:0247-OAGA08728-100ULSize:100 µL
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
CAS Number
9007-83-4
Gene Name
BRCA2, DNA repair associated
Gene Aliases
FAD, FACD, FAD1, GLM3, BRCC2, FANCD, PNCA2, FANCD1, XRCC11, BROVCA2
Gene ID
675
Accession Number
NP_000050.2
Reactivity
Human
Immunogen
Amino acids 2336-2478 of human BRCA2 expressed in E. coli. BRCA2-P400.
Target
Inherited mutations in BRCA1 and this gene, BRCA2, confer increased lifetime risk of developing breast or ovarian cancer. Both BRCA1 and BRCA2 are involved in maintenance of genome stability, specifically the homologous recombination pathway for double-strand DNA repair. The BRCA2 protein contains several copies of a 70 aa motif called the BRC motif, and these motifs mediate binding to the RAD51 recombinase which functions in DNA repair. BRCA2 is considered a tumor suppressor gene, as tumors with BRCA2 mutations generally exhibit loss of heterozygosity (LOH) of the wild-type allele.
Clonality
Monoclonal
Clone
5F6
Type
Monoclonal Antibody
Applications
IHC, IHC-F, IHC-P, WB
Purification
Protein G purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
1 mg/ml
Format
Liquid
Buffer
Phosphate-buffered saline, pH 7.2, no preservative added.
Reconstitution
Keep as concentrated solution. Store at 4C short term. For extended storage aliquot and store at -20C or below. Avoid freeze-thaw cycles.
Fragment
IgG1
NCBI Gene Symbol
BRCA2
Host or Source
Mouse
Protein Name
Breast cancer type 2 susceptibility protein
Gene Name URL
BRCA2
Nucleotide Accession Number
NM_000059.3

Related Products

CatalogName
OPCD01715-200UGBRCA2 Recombinant Protein
OPCD01716-200UGBRCA2 Recombinant Protein
OPCD01715-50UGBRCA2 Recombinant Protein
OPCD01714-200UGBRCA2 Recombinant Protein
OPCD01714-50UGBRCA2 Recombinant Protein
OPCD01716-50UGBRCA2 Recombinant Protein
OPCD01715-10UGBRCA2 Recombinant Protein
OPCD01714-10UGBRCA2 Recombinant Protein
OPCD01716-10UGBRCA2 Recombinant Protein
OKEH04838-96WBRCA2 ELISA Kit (Human)

Alternative Products

CatalogName
MBS9403145-01BRCA2 Antibody

Popular Products