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ATR Antibody

CAT: 0247-OAGA08722-100ULSize: 100 µLDry Ice: NoHazardous: No
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CAT#:0247-OAGA08722-100ULSize:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Gene Name
ATR serine/threonine kinase
Gene Aliases
FRP1, MEC1, SCKL, FCTCS, SCKL1
Gene ID
545
Accession Number
NP_001175.2
Reactivity
Human, Mouse
Immunogen
Recombinant fragment, corresponding to amino acids 710-1100 of Human ATR.
Target
Ataxia Telangiectasia Mutated (ATM) and Rad3-related (ATR) protein is a member of the phosphatidyl-inositol 3-kinase (PI 3-kinase) like family of protein kinases. ATR has a predicted molecular mass of approximately 301 kDa, and it has been shown to be involved in cellular responses to DNA damage. Specifically, it plays a role in checkpoint activation in response to either the presence of stalled replication forks, or by the presence of lesions caused by UV light. Inactivation of ATR is an embryonic lethal event in mice.
Clonality
Monoclonal
Clone
2B5
Type
Monoclonal Antibody
Applications
ICC/IF, IP, WB, FN
Purification
Protein G purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
1 mg/ml
Format
Liquid.// PBS
Reconstitution
Avoid multiple freeze-thaw cycles.//
Molecular Weight
301 kDa
Fragment
IgG1
NCBI Gene Symbol
ATR
Host or Source
Mouse
Protein Name
Serine/threonine-protein kinase ATR
Gene Name URL
ATR
Nucleotide Accession Number
NM_001184.3

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