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SMARCA4 Antibody

CAT: 0247-OAGA08625-100ULSize: 100 µLDry Ice: NoHazardous: No
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CAT#:0247-OAGA08625-100ULSize:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Gene Name
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
Gene Aliases
BRG1, CSS4, SNF2, SWI2, MRD16, RTPS2, BAF190, SNF2L4, SNF2LB, hSNF2b, BAF190A, SNF2-beta
Gene ID
6597
Accession Number
NP_001122316.1
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein encompassing a sequence within the N-terminus region of human BRG1. The exact sequence is proprietary.
Target
The protein encoded by this gene is a member of the SWI/SNF family of proteins and is similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. In addition, this protein can bind BRCA1, as well as regulate the expression of the tumorigenic protein CD44. Mutations in this gene cause rhabdoid tumor predisposition syndrome type 2. Multiple transcript variants encoding different isoforms have been found for this gene.
Clonality
Monoclonal
Clone
GT2712
Type
Monoclonal Antibody
Applications
ICC, IF, IHC-P, WB
Purification
Affinity purified by Protein G.
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
2.44 mg/ml
Format
Liquid
Buffer
PBS
Reconstitution
Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
Fragment
IgG1
NCBI Gene Symbol
SMARCA4
Host or Source
Mouse
Protein Name
Transcription activator BRG1
Gene Name URL
SMARCA4
Nucleotide Accession Number
NM_001128844.1

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