PLS3 Antibody

• Gene Name:

  Plastin 3

• Gene Aliases:

  BMND18, T-plastin

• Gene ID:

  5358

• Accession Number:

  NP_001129497.1

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant protein encompassing a sequence within the center region of human T-Plastin. The exact sequence is proprietary.

• Target:

  Plastins are a family of actin-binding proteins that are conserved throughout eukaryote evolution and expressed in most tissues of higher eukaryotes. In humans, two ubiquitous plastin isoforms (L and T) have been identified. Plastin 1 (otherwise known as Fimbrin) is a third distinct plastin isoform which is specifically expressed at high levels in the small intestine. The L isoform is expressed only in hemopoietic cell lineages, while the T isoform has been found in all other normal cells of solid tissues that have replicative potential (fibroblasts, endothelial cells, epithelial cells, melanocytes, etc.) . The C-terminal 570 amino acids of the T-plastin and L-plastin proteins are 83% identical. It contains a potential calcium-binding site near the N terminus. Alternate splicing results in multiple transcript variants.

• Clonality:

  Monoclonal

• Clone:

  GT3310

• Type:

  Monoclonal Antibody

• Applications:

  ICC, IF, IHC-P, WB

• Purification:

  Affinity purified by Protein A.

• Assay Protocol:

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Concentration:

  2.39 mg/ml

• Format:

  Liquid

• Buffer:

  PBS

• Reconstitution:

  Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

• Fragment:

  IgG2b

• NCBI Gene Symbol:

  PLS3

• Host or Source:

  Mouse

• Protein Name:

  Plastin-3

• Gene Name URL:

  PLS3

• CAS Number:

  9007-83-4

• Nucleotide Accession Number:

  NM_001136025.4