CCT5 Antibody

• Gene Name:

  Chaperonin containing TCP1 subunit 5

• Gene Aliases:

  CCTE, HEL-S-69, PNAS-102, CCT-epsilon, TCP-1-epsilon

• Gene ID:

  22948

• Accession Number:

  NP_001293084.1

• Reactivity:

  Human

• Immunogen:

  Recombinant protein encompassing a sequence within the center region of human TCP1 epsilon. The exact sequence is proprietary.

• Target:

  The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC) . This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Mutations in this gene cause hereditary sensory and autonomic neuropathy with spastic paraplegia (HSNSP) . Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 5 and 13.

• Clonality:

  Monoclonal

• Clone:

  GT639

• Type:

  Monoclonal Antibody

• Applications:

  IP, WB

• Purification:

  Affinity purified by Protein G.

• Assay Protocol:

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Concentration:

  1 mg/ml

• Format:

  Liquid

• Buffer:

  PBS

• Reconstitution:

  Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

• Fragment:

  IgG1

• NCBI Gene Symbol:

  CCT5

• Host or Source:

  Mouse

• Protein Name:

  T-complex protein 1 subunit epsilon

• Gene Name URL:

  CCT5

• CAS Number:

  9007-83-4

• Nucleotide Accession Number:

  NM_001306155.1