LIN28A Antibody

• Gene Name:

  Lin-28 homolog A

• Gene Aliases:

  CSDD1, LIN28, LIN-28, ZCCHC1, lin-28A

• Gene ID:

  79727

• Accession Number:

  NP_078950.1

• Reactivity:

  Human, Mouse

• Immunogen:

  Recombinant protein encompassing a sequence within the center region of human LIN28. The exact sequence is proprietary.

• Target:

  This gene encodes a LIN-28 family RNA-binding protein that acts as a posttranscriptional regulator of genes involved in developmental timing and self-renewal in embryonic stem cells. The encoded protein functions through direct interaction with target mRNAs and by disrupting the maturation of certain miRNAs involved in embryonic development. This protein prevents the terminal processing of the LET7 family of microRNAs which are major regulators of cellular growth and differentiation. Aberrant expression of this gene is associated with cancer progression in multiple tissues.

• Clonality:

  Monoclonal

• Clone:

  GT717

• Type:

  Monoclonal Antibody

• Applications:

  FACS, ICC, IF, IHC-P, WB

• Purification:

  Affinity purified by Protein G.

• Assay Protocol:

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Concentration:

  1 mg/ml

• Format:

  Liquid

• Buffer:

  PBS

• Reconstitution:

  Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

• Fragment:

  IgG2a

• NCBI Gene Symbol:

  LIN28A

• Host or Source:

  Mouse

• Protein Name:

  Protein lin-28 homolog A

• Gene Name URL:

  LIN28A

• CAS Number:

  9007-83-4

• Nucleotide Accession Number:

  NM_024674.5