RAB7A Antibody

• Gene Name:

  RAB7A, member RAS oncogene family

• Gene Aliases:

  RAB7, CMT2B, PRO2706

• Gene ID:

  7879

• Accession Number:

  NP_004628.4

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human Rab7. The exact sequence is proprietary.

• Target:

  RAB family members are small, RAS-related GTP-binding proteins that are important regulators of vesicular transport. Each RAB protein targets multiple proteins that act in exocytic / endocytic pathways. This gene encodes a RAB family member that regulates vesicle traffic in the late endosomes and also from late endosomes to lysosomes. This encoded protein is also involved in the cellular vacuolation of the VacA cytotoxin of Helicobacter pylori. Mutations at highly conserved amino acid residues in this gene have caused some forms of Charcot-Marie-Tooth (CMT) type 2 neuropathies.

• Clonality:

  Polyclonal

• Type:

  Polyclonal Antibody

• Applications:

  ICC, IF, IHC-P, WB

• Purification:

  Purified by antigen-affinity chromatography.

• Assay Protocol:

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Concentration:

  0.36 mg/ml

• Format:

  Liquid

• Buffer:

  1XPBS, 1% BSA, 20% Glycerol (pH7) . 0.025% ProClin 300 was added as a preservative.

• Reconstitution:

  Keep as concentrated solution. Aliquot and store at -20oC or below. Avoid multiple freeze-thaw cycles.

• Fragment:

  IgG

• NCBI Gene Symbol:

  RAB7A

• Host or Source:

  Rabbit

• Protein Name:

  Ras-related protein Rab-7a

• Gene Name URL:

  RAB7A

• CAS Number:

  9007-83-4

• Nucleotide Accession Number:

  NM_004637.5