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SARM1 Antibody

CAT: 0247-OAGA07948-100ULSize: 100 µLDry Ice: NoHazardous: No
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CAT#:0247-OAGA07948-100ULSize:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Gene Name
Sterile alpha and TIR motif containing 1
Gene Aliases
SARM, HsTIR, SAMD2, hSARM1, MyD88-5
Gene ID
23098
Accession Number
NP_055892.2
Reactivity
Human, Drosophilia
Immunogen
Recombinant protein encompassing a sequence within the C-terminus region of human SARM1. The exact sequence is proprietary.
Target
Involved in innate immnune response. Acts as a negative regulator of TICAM1/TRIF-dependent Toll-like receptor signaling by inhibiting induction of TLR3- and TLR4-dependent genes. Specifically blocks TICAM1/TRIF-dependent transcription-factor activation and gene induction, without affecting the MYD88-dependent pathway or non-TLR signaling. Negative regulator of NF-kappa-B and IRF activation.
Clonality
Polyclonal
Type
Polyclonal Antibody
Applications
ICC, IF, IHC-P, WB
Purification
Purified by antigen-affinity chromatography.
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
Varies by lot. See vial for concentration.
Homology
Rhesus Monkey (>80% identity)
Format
Liquid.// 1XPBS, 1% BSA, 20% glycerol (pH 7) with 0.025% Proclin300 added as a preservative
Reconstitution
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4° C. For long-term storage, aliquot and store at -20° C or below. Avoid multiple freeze-thaw cycles.
Molecular Weight
79 kDa
Fragment
IgG
NCBI Gene Symbol
SARM1
Host or Source
Rabbit
Protein Name
Sterile alpha and TIR motif-containing protein 1
Gene Name URL
SARM1
Nucleotide Accession Number
NM_015077.3

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