EIF2AK2 Antibody

• Gene Name :

  Eukaryotic translation initiation factor 2 alpha kinase 2

• Gene Aliases :

  PKR, PRKR, LEUDEN, EIF2AK1, PPP1R83

• Gene ID :

  5610

• Accession Number :

  NP_001129123.1

• Reactivity :

  Human

• Immunogen :

  Recombinant protein encompassing a sequence within the center region of human PKR. The exact sequence is proprietary.

• Target :

  The protein encoded by this gene is a serine/threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. This protein is also activated by manganese ions and heparin. Three transcript variants encoding two different isoforms have been found for this gene.

• Clonality :

  Polyclonal

• Type :

  Polyclonal Antibody

• Applications :

  IHC-P, IP, WB

• Purification :

  Purified by antigen-affinity chromatography.

• Assay Protocol :

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Concentration :

  1 mg/ml

• Format :

  Liquid

• Buffer :

  1XPBS, 20% Glycerol (pH7) . 0.025% ProClin 300 was added as a preservative.

• Reconstitution :

  Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

• Fragment :

  IgG

• NCBI Gene Symbol :

  EIF2AK2

• Host or Source :

  Rabbit

• Protein Name :

  Interferon-induced, double-stranded RNA-activated protein kinase

• Gene Name URL :

  EIF2AK2

• CAS Number :

  9007-83-4

• Nucleotide Accession Number :

  NM_001135651.2