EIF2AK2 Antibody

CAT: 0247-OAGA07863-100ULSize: 100 µLDry Ice: NoHazardous: No
CAT#:0247-OAGA07863-100ULSize:100 µL
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CAS Number
9007-83-4
Gene Name
Eukaryotic translation initiation factor 2 alpha kinase 2
Gene Aliases
PKR, PRKR, LEUDEN, EIF2AK1, PPP1R83
Gene ID
5610
Accession Number
NP_001129123.1
Reactivity
Human
Immunogen
Recombinant protein encompassing a sequence within the center region of human PKR. The exact sequence is proprietary.
Target
The protein encoded by this gene is a serine/threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. This protein is also activated by manganese ions and heparin. Three transcript variants encoding two different isoforms have been found for this gene.
Clonality
Polyclonal
Type
Polyclonal Antibody
Applications
IHC-P, IP, WB
Purification
Purified by antigen-affinity chromatography.
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
1 mg/ml
Format
Liquid
Buffer
1XPBS, 20% Glycerol (pH7) . 0.025% ProClin 300 was added as a preservative.
Reconstitution
Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
Fragment
IgG
NCBI Gene Symbol
EIF2AK2
Host or Source
Rabbit
Protein Name
Interferon-induced, double-stranded RNA-activated protein kinase
Gene Name URL
EIF2AK2
Nucleotide Accession Number
NM_001135651.2

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