DOCK2 Antibody

• Gene Name:

  Dedicator of cytokinesis 2

• Gene Aliases:

  IMD40

• Gene ID:

  1794

• Accession Number:

  NP_004937.1

• Reactivity:

  Human

• Immunogen:

  Recombinant protein encompassing a sequence within the C-terminus region of human DOCK2. The exact sequence is proprietary.

• Target:

  The protein encoded by this gene belongs to the CDM protein family. It is specifically expressed in hematopoietic cells and is predominantly expressed in peripheral blood leukocytes. The protein is involved in remodeling of the actin cytoskeleton required for lymphocyte migration in response to chemokine signaling. It activates members of the Rho family of GTPases, for example RAC1 and RAC2, by acting as a guanine nucleotide exchange factor (GEF) to exchange bound GDP for free GTP.

• Clonality:

  Polyclonal

• Type:

  Polyclonal Antibody

• Applications:

  ICC, IF, WB

• Purification:

  Purified by antigen-affinity chromatography.

• Assay Protocol:

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Concentration:

  0.49 mg/ml

• Format:

  Liquid

• Buffer:

  1XPBS, 1% BSA, 20% Glycerol (pH7) . 0.025% ProClin 300 was added as a preservative.

• Reconstitution:

  Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

• Fragment:

  IgG

• NCBI Gene Symbol:

  DOCK2

• Host or Source:

  Rabbit

• Protein Name:

  Dedicator of cytokinesis protein 2

• Gene Name URL:

  DOCK2

• CAS Number:

  9007-83-4

• Nucleotide Accession Number:

  NM_004946.2