MAP4K4 Antibody

• Gene Name :

  Mitogen-activated protein kinase kinase kinase kinase 4

• Gene Aliases :

  HGK, NIK, MEKKK4, FLH21957, HEL-S-31

• Gene ID :

  9448

• Accession Number :

  NP_001229488.1

• Reactivity :

  Human

• Immunogen :

  Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human MAP4K4. The exact sequence is proprietary.

• Target :

  The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase has been shown to specifically activate MAPK8/JNK. The activation of MAPK8 by this kinase is found to be inhibited by the dominant-negative mutants of MAP3K7/TAK1, MAP2K4/MKK4, and MAP2K7/MKK7, which suggests that this kinase may function through the MAP3K7-MAP2K4-MAP2K7 kinase cascade, and mediate the TNF-alpha signaling pathway. Alternatively spliced transcript variants encoding different isoforms have been identified.

• Clonality :

  Polyclonal

• Type :

  Polyclonal Antibody

• Applications :

  ICC, IF, IHC-P, WB

• Purification :

  Purified by antigen-affinity chromatography.

• Assay Protocol :

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Concentration :

  0.62 mg/ml

• Format :

  Liquid

• Buffer :

  0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7) . 0.01% Thimerosal was added as a preservative.

• Reconstitution :

  Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

• Fragment :

  IgG

• NCBI Gene Symbol :

  MAP4K4

• Host or Source :

  Rabbit

• Protein Name :

  Mitogen-activated protein kinase kinase kinase kinase 4

• Gene Name URL :

  MAP4K4

• CAS Number :

  9007-83-4

• Nucleotide Accession Number :

  NM_001242559.1