AIFM1 Antibody

• Gene Name:

  Apoptosis inducing factor mitochondria associated 1

• Gene Aliases:

  AIF, AUNX1, CMT2D, CMTX4, COWCK, DFNX5, NADMR, NAMSD, PDCD8, COXPD6, SEMDHL

• Gene ID:

  9131

• Accession Number:

  NP_001124318.2

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant protein encompassing a sequence within the center region of human AIF. The exact sequence is proprietary.

• Target:

  This gene encodes a flavoprotein essential for nuclear disassembly in apoptotic cells that is found in the mitochondrial intermembrane space in healthy cells. Induction of apoptosis results in the translocation of this protein to the nucleus where it effects chromosome condensation and fragmentation. In addition, this gene product induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9. Several alternative transcripts encoding different isoforms have been identified for this gene.

• Clonality:

  Polyclonal

• Type:

  Polyclonal Antibody

• Applications:

  ICC, IF, IHC-FFPE, WB

• Purification:

  Purified by antigen-affinity chromatography.

• Assay Protocol:

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Concentration:

  1 mg/ml

• Homology:

  Zebrafish (80%), Pig (97%), Chicken (84%), Rhesus Monkey (99%), Bovine (95%)

• Format:

  Liquid// 0.1M Tris, 0.1M Glycine, 10% glycerol (pH 7) with 0.01% Thimerosal as a preservative

• Reconstitution:

  Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

• Molecular Weight:

  67 kDa

• Fragment:

  IgG

• NCBI Gene Symbol:

  AIFM1

• Host or Source:

  Rabbit

• Protein Name:

  Apoptosis-inducing factor 1, mitochondrial

• Gene Name URL:

  AIFM1

• CAS Number:

  9007-83-4

• Nucleotide Accession Number:

  NM_001130846.3