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AIFM1 Antibody

CAT: 0247-OAGA04280-100ULSize: 100 µLDry Ice: NoHazardous: No
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CAT#:0247-OAGA04280-100ULSize:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Gene Name
Apoptosis inducing factor mitochondria associated 1
Gene Aliases
AIF, AUNX1, CMT2D, CMTX4, COWCK, DFNX5, NADMR, NAMSD, PDCD8, COXPD6, SEMDHL
Gene ID
9131
Accession Number
NP_001124318.2
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein encompassing a sequence within the center region of human AIF. The exact sequence is proprietary.
Target
This gene encodes a flavoprotein essential for nuclear disassembly in apoptotic cells that is found in the mitochondrial intermembrane space in healthy cells. Induction of apoptosis results in the translocation of this protein to the nucleus where it effects chromosome condensation and fragmentation. In addition, this gene product induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9. Several alternative transcripts encoding different isoforms have been identified for this gene.
Clonality
Polyclonal
Type
Polyclonal Antibody
Applications
ICC, IF, IHC-FFPE, WB
Purification
Purified by antigen-affinity chromatography.
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
1 mg/ml
Homology
Zebrafish (80%), Pig (97%), Chicken (84%), Rhesus Monkey (99%), Bovine (95%)
Format
Liquid// 0.1M Tris, 0.1M Glycine, 10% glycerol (pH 7) with 0.01% Thimerosal as a preservative
Reconstitution
Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
Molecular Weight
67 kDa
Fragment
IgG
NCBI Gene Symbol
AIFM1
Host or Source
Rabbit
Protein Name
Apoptosis-inducing factor 1, mitochondrial
Gene Name URL
AIFM1
Nucleotide Accession Number
NM_001130846.3

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