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SP1 Antibody

CAT: 0247-OAGA03622-100ULSize: 100 µLDry Ice: NoHazardous: No
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CAT#:0247-OAGA03622-100ULSize:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Gene Name
Sp1 transcription factor
Gene Aliases
Sp1 transcription factor
Gene ID
6667
Accession Number
NP_001238754.1
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein encompassing a sequence within the center region of human SP1. The exact sequence is proprietary.
Target
Transcription factor that can activate or repress transcription in response to physiological and pathological stimuli. Binds with high affinity to GC-rich motifs and regulates the expression of a large number of genes involved in a variety of processes such as cell growth, apoptosis, differentiation and immune responses. Highly regulated by post-translational modifications (phosphorylations, sumoylation, proteolytic cleavage, glycosylation and acetylation) . Binds also the PDGFR-alpha G-box promoter. May have a role in modulating the cellular response to DNA damage. Implicated in chromatin remodeling. Plays a role in the recruitment of SMARCA4/BRG1 on the c-FOS promoter. Plays an essential role in the regulation of FE65 gene expression.
Clonality
Polyclonal
Type
Polyclonal Antibody
Applications
WB, ICC, IF, IHC-P, IP, ChIP assay
Purification
Purified by antigen-affinity chromatography
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
0.06 mg/ml
Homology
Bovine, Rhesus Monkey (>80% identity)
Format
Liquid.// 1XPBS, 1% BSA, 20% Glycerol (pH7) . 0.025% ProClin 300 was added as a preservative.
Buffer
1XPBS, 20% Glycerol (pH7) . 0.025% ProClin 300 was added as a preservative.
Reconstitution
Keep as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4° C. For long-term storage, aliquot and store at -20° C or below. Avoid multiple freeze-thaw cycles.
Molecular Weight
81 kDa
Fragment
IgG
NCBI Gene Symbol
SP1
Host or Source
Rabbit
Protein Name
Transcription factor Sp1
Gene Name URL
SP1
Nucleotide Accession Number
NM_001251825.1

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