DKC1 Antibody

• CAS Number :

  9007-83-4

• Gene Name :

  Dyskerin pseudouridine synthase 1

• Gene Aliases :

  DKC, CBF5, DKCX, NAP57, NOLA4, XAP101

• Gene ID :

  1736

• Accession Number :

  NP_001135935.1

• Reactivity :

  Human

• Immunogen :

  Recombinant protein encompassing a sequence within the center region of human DKC1. The exact sequence is proprietary.

• Target :

  This gene functions in two distinct complexes. It plays an active role in telomerase stabilization and maintenance, as well as recognition of snoRNAs containing H/ACA sequences which provides stability during biogenesis and assembly into H/ACA small nucleolar RNA ribonucleoproteins (snoRNPs) . This gene is highly conserved and widely expressed, and may play additional roles in nucleo-cytoplasmic shuttling, DNA damage response, and cell adhesion. Mutations have been associated with X-linked dyskeratosis congenita. Alternative splicing results in multiple transcript variants.

• Clonality :

  Polyclonal

• Type :

  Polyclonal Antibody

• Applications :

  ICC, IF, IHC-P, IP, WB

• Purification :

  Purified by antigen-affinity chromatography.

• Assay Protocol :

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Concentration :

  1 mg/ml

• Format :

  Liquid

• Buffer :

  1XPBS, 1% BSA, 20% Glycerol (pH7) . 0.01% Thimerosal was added as a preservative.

• Reconstitution :

  Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

• Fragment :

  IgG

• NCBI Gene Symbol :

  DKC1

• Host or Source :

  Rabbit

• Protein Name :

  H/ACA ribonucleoprotein complex subunit 4

• Gene Name URL :

  DKC1

• Nucleotide Accession Number :

  NM_001142463.2