Products for Research Use Only
RegisterLogin

UHRF1 Antibody

CAT: 0247-OAGA02225-100ULSize: 100 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0247-OAGA02225-100ULSize:100 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
9007-83-4
Gene Name
Ubiquitin-like with PHD and ring finger domains 1
Gene Aliases
Np95, hNP95, ICBP90, RNF106, TDRD22, hUHRF1, huNp95
Gene ID
29128
Reactivity
Human
Immunogen
Recombinant protein encompassing a sequence within the center region of human UHRF1. The exact sequence is proprietary.
Target
This gene encodes a member of a subfamily of RING-finger type E3 ubiquitin ligases. The protein binds to specific DNA sequences, and recruits a histone deacetylase to regulate gene expression. Its expression peaks at late G1 phase and continues during G2 and M phases of the cell cycle. It plays a major role in the G1/S transition by regulating topoisomerase IIalpha and retinoblastoma gene expression, and functions in the p53-dependent DNA damage checkpoint. It is regarded as a hub protein for the integration of epigenetic information. This gene is up-regulated in various cancers, and it is therefore considered to be a therapeutic target. Multiple transcript variants encoding different isoforms have been found for this gene. A related pseudogene exists on chromosome 12.
Clonality
Polyclonal
Type
Polyclonal Antibody
Applications
IF, IHC-P, WB
Purification
Purified by antigen-affinity chromatography.
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
1mg/ml
Format
Liquid. 1XPBS, 1%BSA, 20% Glycerol (pH7) . 0.01% Thimerosal was added as a preservative.
Reconstitution
Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
Fragment
IgG
NCBI Gene Symbol
UHRF1
Host or Source
Rabbit
Gene Name URL
UHRF1

Related Products

CatalogName
OCOA11432-20UGUHRF1 Protein Lysate
OCOA15076-20UGUHRF1 Protein Lysate
AAP32596-100UGUHRF1 Peptide - C-terminal region (AAP32596)
AAP39021-100UGUHRF1 Peptide - N-terminal region (AAP39021)
OAAN00806-50ULUHRF2 Antibody
OAAN00806-100ULUHRF2 Antibody
OAAJ07404-100ULUHRF2 Antibody
OAAN00806-200ULUHRF2 Antibody
ARP34620_P050-25ULUHRF2 Antibody - middle region
ARP34620_P050UHRF2 antibody - middle region (ARP34620_P050)

Alternative Products

CatalogName
GWB-MM948CUHRF1 Antibody
ABD6929UHRF1 Antibody

Popular Products