DPYD antibody

• Gene Name:

  Dihydropyrimidine dehydrogenase [NADP (+) ]

• Gene Aliases:

  DHP, DPD, DHPDHASE

• Gene ID:

  1806

• Accession Number:

  NP_000101.2

• Reactivity:

  Human

• Immunogen:

  Recombinant protein encompassing a sequence within the center region of human DPYD. The exact sequence is proprietary.

• Target:

  The protein encoded by this gene is a pyrimidine catabolic enzyme and the initial and rate-limiting factor in the pathway of uracil and thymidine catabolism. Mutations in this gene result in dihydropyrimidine dehydrogenase deficiency, an error in pyrimidine metabolism associated with thymine-uraciluria and an increased risk of toxicity in cancer patients receiving 5-fluorouracil chemotherapy.

• Clonality:

  Polyclonal

• Type:

  Polyclonal Antibody

• Applications:

  WB, IHC-P

• Purification:

  Purified by antigen-affinity chromatography.

• Assay Protocol:

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Concentration:

  0.59 mg/ml

• Homology:

  Mouse, Rat, Bovine, Pig, Xenopus laevis (>80% identity)

• Format:

  Liquid.// 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH 7) . 0.01% Thimerosal was added as a preservative.

• Reconstitution:

  Keep as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4° C. For long-term storage, aliquot and store at -20° C or below. Avoid multiple freeze-thaw cycles.

• Molecular Weight:

  111 kDa

• Fragment:

  IgG

• NCBI Gene Symbol:

  DPYD

• Host or Source:

  Rabbit

• Protein Name:

  Dihydropyrimidine dehydrogenase [NADP (+) ]

• Gene Name URL:

  DPYD

• CAS Number:

  9007-83-4