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DPYD antibody

CAT: 0247-OAGA01037-100ULSize: 100 µLDry Ice: NoHazardous: No
CAT#:0247-OAGA01037-100ULSize:100 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Gene Name
Dihydropyrimidine dehydrogenase [NADP (+) ]
Gene Aliases
DHP, DPD, DHPDHASE
Gene ID
1806
Accession Number
NP_000101.2
Reactivity
Human
Immunogen
Recombinant protein encompassing a sequence within the center region of human DPYD. The exact sequence is proprietary.
Target
The protein encoded by this gene is a pyrimidine catabolic enzyme and the initial and rate-limiting factor in the pathway of uracil and thymidine catabolism. Mutations in this gene result in dihydropyrimidine dehydrogenase deficiency, an error in pyrimidine metabolism associated with thymine-uraciluria and an increased risk of toxicity in cancer patients receiving 5-fluorouracil chemotherapy.
Clonality
Polyclonal
Type
Polyclonal Antibody
Applications
WB, IHC-P
Purification
Purified by antigen-affinity chromatography.
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
0.59 mg/ml
Homology
Mouse, Rat, Bovine, Pig, Xenopus laevis (>80% identity)
Format
Liquid.// 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH 7) . 0.01% Thimerosal was added as a preservative.
Reconstitution
Keep as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4° C. For long-term storage, aliquot and store at -20° C or below. Avoid multiple freeze-thaw cycles.
Molecular Weight
111 kDa
Fragment
IgG
NCBI Gene Symbol
DPYD
Host or Source
Rabbit
Protein Name
Dihydropyrimidine dehydrogenase [NADP (+) ]
Gene Name URL
DPYD

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