DPYD antibody

• Gene Name :

  Dihydropyrimidine dehydrogenase [NADP (+) ]

• Gene Aliases :

  DHP, DPD, DHPDHASE

• Gene ID :

  1806

• Accession Number :

  NP_000101.2

• Reactivity :

  Human

• Immunogen :

  Recombinant protein encompassing a sequence within the center region of human DPYD. The exact sequence is proprietary.

• Target :

  The protein encoded by this gene is a pyrimidine catabolic enzyme and the initial and rate-limiting factor in the pathway of uracil and thymidine catabolism. Mutations in this gene result in dihydropyrimidine dehydrogenase deficiency, an error in pyrimidine metabolism associated with thymine-uraciluria and an increased risk of toxicity in cancer patients receiving 5-fluorouracil chemotherapy.

• Clonality :

  Polyclonal

• Type :

  Polyclonal Antibody

• Applications :

  WB, IHC-P

• Purification :

  Purified by antigen-affinity chromatography.

• Assay Protocol :

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Concentration :

  0.59 mg/ml

• Homology :

  Mouse, Rat, Bovine, Pig, Xenopus laevis (>80% identity)

• Format :

  Liquid.// 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH 7) . 0.01% Thimerosal was added as a preservative.

• Reconstitution :

  Keep as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4° C. For long-term storage, aliquot and store at -20° C or below. Avoid multiple freeze-thaw cycles.

• Molecular Weight :

  111 kDa

• Fragment :

  IgG

• NCBI Gene Symbol :

  DPYD

• Host or Source :

  Rabbit

• Protein Name :

  Dihydropyrimidine dehydrogenase [NADP (+) ]

• Gene Name URL :

  DPYD

• CAS Number :

  9007-83-4