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SNAP5089

CAT: 0804-HY-103202ASize: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-103202ASize:1 Each
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Description
SNAP5089 is a selective α1A-adrenoceptor antagonist with over 1700-fold selectivity for the α1A subtype, which may have implications for the treatment of hypertension and benign prostatic hypertrophy. SNAP5089 demonstrates significant receptor affinity compared to other clinical drugs, emphasizing its potential therapeutic advantages. SNAP5089's high affinity aligns with its suitability for conditions where precise α1A modulation is desirable.
CAS Number
157066-76-7
UNSPSC
12352005
Target
Adrenergic Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/snap5089-free-base.html
Smiles
O=C(C1=C(C)NC(C)=C(C(NCCCN2CCC(C3=CC=CC=C3)(C4=CC=CC=C4)CC2)=O)C1C5=CC=C([N+]([O-])=O)C=C5)OC
Molecular Formula
C36H40N4O5
Molecular Weight
608.73
References & Citations
[1]The affinity and selectivity of α-adrenoceptor antagonists, antidepressants, and antipsychotics for the human α1A, α1B, and α1D-adrenoceptors
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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