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LTBP4 antibody

CAT: 0247-OAGA00117-100ULSize: 100 µLDry Ice: NoHazardous: No
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CAT#:0247-OAGA00117-100ULSize:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Gene Name
Latent-transforming growth factor beta-binding protein 4
Gene Aliases
ARCL1C, LTBP-4, LTBP4L, LTBP4S
Gene ID
8425
Accession Number
NP_001036009.1
Reactivity
Human, Mouse
Immunogen
Recombinant protein encompassing a sequence within the N-terminus region of human LTBP4. The exact sequence is proprietary.
Target
Transforming growth factor-beta, or TGFB (see TGFB1; MIM 190180), remains biologically latent after secretion, blocked from activity by its N-terminal propeptide (the latency-associated peptide, or LAP) . TGFB is activated by its dissociation from LAP. The latent form of TGFB is secreted in association with a latent TGFB-binding protein, or LTBP (see LTBP1; MIM 150390), and assembled into the extracellular matrix. LTBPs are mainly composed of epidermal growth factor (EGF; MIM 131530) -like repeats and protein domains with 8-cysteine repeats, both of which are also found in fibrillins (e.g., MIM 134797) . See Oklu and Hesketh (2000) [PubMed 11104663] for a review of the LTBP gene family.[supplied by OMIM]
Clonality
Polyclonal
Type
Polyclonal Antibody
Applications
ICC, IF, IHC-FFPE, WB
Purification
Purified by antigen-affinity chromatography.
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
0.25 mg/ml
Homology
Rat (97%)
Format
Liquid.// 1X PBS, 1% BSA, 20% glycerol (pH 7) with 0.025% Proclin300 as a preservative
Molecular Weight
173 kDa
Fragment
IgG
NCBI Gene Symbol
LTBP4
Host or Source
Rabbit
Protein Name
Latent-transforming growth factor beta-binding protein 4
Gene Name URL
LTBP4

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