CD86 Antibody

CAT: 0247-OAEE00991-100TSize: 100 TestsDry Ice: NoHazardous: No
CAT#:0247-OAEE00991-100TSize:100 Tests
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CAS Number
9007-83-4
Gene Name
CD86 molecule
Gene Aliases
Activation B7-2 antigen; B7.2; B70; B7-2; B-lymphocyte activation antigen B7-2; BU63; CD28LG2; CD86 antigen (CD28 antigen ligand 2, B7-2 antigen) ; CTLA-4 counter-receptor B7.2; FUN-1; LAB72; T-lymphocyte activation antigen CD86.
Gene ID
942
Accession Number
NP_001193853.1NP_001193854.1NP_008820.3NP_787058.4NP_795711.1
Reactivity
Human
Immunogen
B-lymphoblastoid cell line ARH 77
Target
Receptor involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or CTLA-4. May play a critical role in the early events of T-cell activation and costimulation of naive T-cells, such as deciding between immunity and anergy that is made by T-cells within 24 hours after activation. Isoform 2 interferes with the formation of CD86 clusters, and thus acts as a negative regulator of T-cell activation.
Clonality
Monoclonal
Clone
BU63
Conjugation
PerCP
Type
Monoclonal Antibody
Applications
Flow cytometry
Purification
Purified by size-exclusion chromatography
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
10 ul / test
Format
Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Buffer
The reagent is provided in phosphate buffered saline (PBS) containing 15 mM sodium azide and 0.2% (w/v) high-grade protease free Bovine Serum Albumin (BSA) as a stabilizing agent.
Reconstitution
2°C to 8°C
Fragment
IgG1
Specificity
HLDA V; WS Code BP BP072 HLDA V; WS Code A A109 HLDA VI; WS Code BP 95 HLDA VI; WS Code B CD86.9//
NCBI Gene Symbol
CD86
Host or Source
Mouse
Protein Name
T-lymphocyte activation antigen CD86
Gene Name URL
CD86
Nucleotide Accession Number
NM_001206924.1NM_001206925.1NM_006889.4NM_175862.4NM_176892.1